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The next frontier for innovation,
research, clinical trials, and state-of-the art treatment.

Our history of research and innovation has resulted in many of the diagnostic and therapeutic techniques currently used around the world to treat cancer and blood disorders. Today, we continue to stand among the world’s leaders in many innovative approaches.

Our Researchers

at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center


Bauer Lab
The laboratory studies the genetic determinants of blood cell ontogeny and disease. The blood system recapitulates fundamental biologic activities, such as renewal/differentiation, regeneration/homeostasis, and development/aging. We use molecular genetic, biochemical,…

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Luca Biasco Lab
Using barcoding for the in vivo clonal tracking of genetically engineered cells and retroviral scanning for the characterization of cellular genetic and nuclear identity Our laboratory seeks to elucidate the…

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Carla Kim Lab
The broad interest of the Kim Lab is to characterize the biology of stem cells in normal lung and lung cancer. Numerous lung diseases such as cystic fibrosis or chronic…

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Croker Lab
The laboratory studies immunomodulatory forms of cell death including pyroptosis and necroptosis. The role of these novel cell death pathways is investigated during hematopoietic stress induced by infection, chemotherapy, transplantation…

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Knoechel Lab
Our research efforts focus on identifying epigenetic dependencies in pediatric tumors with a particular focus on high risk pediatric leukemias and sarcomas. Defects in chromatin and aberrant epigenetic regulation and…

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Center for Platelet Research Studies
The Center for Platelet Research Studies is an internationally recognized multidisciplinary center for the study of platelet function by state-of-the-art methods. The Center undertakes basic, translational, and clinical research, including…

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Orkin Lab
The Orkin laboratory focuses on stem cell biology, particularly the development and function of the blood system, the relationship between cancer and stem cells, and the mechanisms responsible for self-renewal…

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Paw Lab
The focus of Barry Paw’s laboratory research is studying genes important for red cell and platelet development using the zebrafish as a genetic model organism. The genetic program for development…

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Sankaran Laboratory
The Sankaran laboratory uses human genetic studies to gain insight into normal hematopoiesis and how this process is perturbed in disease. Our studies are relevant to numerous blood diseases, including…

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Shimamura Lab
The broad interest of the Shimamura lab is the genetic and molecular mechanisms regulating hematopoiesis and clonal evolution to MDS and leukemia. The Shimamura lab studies inherited bone marrow failure…

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The Alejandro Gutierrez Lab
Our laboratory’s primary interest lies in unraveling the molecular pathogenesis of human cancer, with a focus on discovery of novel therapeutic targets in chemoresistant human cancers. Our approach combines analysis…

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Williams Laboratory
The major interest of the Williams laboratory is the biology of hematopoietic stem cells. The work has focused on understanding the interaction of hematopoietic stem cells with the bone marrow…

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Walensky Laboratory
The Walensky laboratory focuses on the chemical biology of deregulated apoptotic and transcriptional pathways in cancer. In particular, the lab’s studies emphasize the chemical, structural, and cell biology of the…

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Weinstock Laboratory
The Weinstock Laboratory uses a range of approaches at the intersection of genetics, DNA repair, and mouse modeling to address the ontogeny, pathogenesis, and therapeutic targeting of lymphoid neoplasms.

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Bauer Lab
The laboratory studies the genetic determinants of blood cell ontogeny and disease. The blood system recapitulates fundamental biologic activities, such as renewal/differentiation, regeneration/homeostasis, and development/aging. We use molecular genetic, biochemical,…
Read More
Luca Biasco Lab
Using barcoding for the in vivo clonal tracking of genetically engineered cells and retroviral scanning for the characterization of cellular genetic and nuclear identity Our laboratory seeks to elucidate the…
Read More
Carla Kim Lab
The broad interest of the Kim Lab is to characterize the biology of stem cells in normal lung and lung cancer. Numerous lung diseases such as cystic fibrosis or chronic…
Read More
Croker Lab
The laboratory studies immunomodulatory forms of cell death including pyroptosis and necroptosis. The role of these novel cell death pathways is investigated during hematopoietic stress induced by infection, chemotherapy, transplantation…
Read More
Knoechel Lab
Our research efforts focus on identifying epigenetic dependencies in pediatric tumors with a particular focus on high risk pediatric leukemias and sarcomas. Defects in chromatin and aberrant epigenetic regulation and…
Read More
Center for Platelet Research Studies
The Center for Platelet Research Studies is an internationally recognized multidisciplinary center for the study of platelet function by state-of-the-art methods. The Center undertakes basic, translational, and clinical research, including…
Read More
Orkin Lab
The Orkin laboratory focuses on stem cell biology, particularly the development and function of the blood system, the relationship between cancer and stem cells, and the mechanisms responsible for self-renewal…
Read More
Paw Lab
The focus of Barry Paw’s laboratory research is studying genes important for red cell and platelet development using the zebrafish as a genetic model organism. The genetic program for development…
Read More
Sankaran Laboratory
The Sankaran laboratory uses human genetic studies to gain insight into normal hematopoiesis and how this process is perturbed in disease. Our studies are relevant to numerous blood diseases, including…
Read More
Shimamura Lab
The broad interest of the Shimamura lab is the genetic and molecular mechanisms regulating hematopoiesis and clonal evolution to MDS and leukemia. The Shimamura lab studies inherited bone marrow failure…
Read More
The Alejandro Gutierrez Lab
Our laboratory’s primary interest lies in unraveling the molecular pathogenesis of human cancer, with a focus on discovery of novel therapeutic targets in chemoresistant human cancers. Our approach combines analysis…
Read More
Williams Laboratory
The major interest of the Williams laboratory is the biology of hematopoietic stem cells. The work has focused on understanding the interaction of hematopoietic stem cells with the bone marrow…
Read More

Our Researchers in the News

Gene therapy trial gives Coopersville toddler second chance at life

Colton was born healthy almost two years ago, but his fraternal twin brother, Levi, was not. The Michigan toddler had severe combined immune deficiency – “bubble boy” disease – discovered through newborn screening, Fox 17 reports from Grand Rapids.

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New Chief Scientific Officer at Boston Children’s Hospital

Boston Children’s Hospital has established a new executive role to focus on research, the hospital announced. Dr. David Williams, who serves as chief of hematology and oncology and director of clinical and translational research at Boston Children’s Hospital, will serve as chief scientific officer.

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Childhood cancer deaths: Brain cancer overtakes leukemia as top cause

Leukemia is no longer the No. 1 cause of cancer deaths in children, but brain cancer has taken it's place, according to a new report.

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