Publications
Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci.
Canver MC, Lessard S, Pinello L, Wu Y, Ilboudo Y, Stern EN, Needleman AJ, Galactéros F, Brugnara C, Kutlar A, McKenzie C, Reid M, Chen DD, Das PP, Cole M, Zeng J, Kurita R, Nakamura Y, Yuan GC, G L, Bauer D*, Orkin S*
CRISPResso: sequencing analysis toolbox for CRISPR genome editing.
Pinello L*, Canver MC, Hoban MD, Orkin SH, Kohn DB, Bauer D*, Yuan G*
BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis.
Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, Maeda T, Yuan GC, Zhang F*, Orkin S*, Bauer D*
Issue: 31 Volume: 289 Page: 21312-24
Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells.
Canver M*, Bauer D*, Dass A, Yien YY, Chung J, Masuda T, Maeda T, Paw B, Orkin SH
Issue: 6155 Volume: 342 Page: 253-7
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.
Bauer D, Kamran SC, Lessard S, Xu J, Fujiwara Y, Lin C, Shao Z, Canver MC, Smith EC, Pinello L, Sabo PJ, Vierstra J, Voit RA, Yuan GC, Porteus MH, Stamatoyannopoulos JA, Lettre G, Orkin SH