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Publications

Journal Article: Nature Genetics Year: 2017

Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci. 

Canver MC, Lessard S, Pinello L, Wu Y, Ilboudo Y, Stern EN, Needleman AJ, Galactéros F, Brugnara C, Kutlar A, McKenzie C, Reid M, Chen DD, Das PP, Cole M, Zeng J, Kurita R, Nakamura Y, Yuan GC, G L, Bauer D*, Orkin S*
Journal Article: Nature Biotechnology Year: 2016

CRISPResso: sequencing analysis toolbox for CRISPR genome editing. 

Pinello L*, Canver MC, Hoban MD, Orkin SH, Kohn DB, Bauer D*, Yuan G*
Journal Article: Nature Year: 2015

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis. 

Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, Maeda T, Yuan GC, Zhang F*, Orkin S*, Bauer D*
Journal Article: The Journal of biological chemistry Year: 2014
Issue: 31 Volume: 289 Page: 21312-24

Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells. 

Canver M*, Bauer D*, Dass A, Yien YY, Chung J, Masuda T, Maeda T, Paw B, Orkin SH
Journal Article: Science (New York, N.Y.) Year: 2013
Issue: 6155 Volume: 342 Page: 253-7

An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level. 

Bauer D, Kamran SC, Lessard S, Xu J, Fujiwara Y, Lin C, Shao Z, Canver MC, Smith EC, Pinello L, Sabo PJ, Vierstra J, Voit RA, Yuan GC, Porteus MH, Stamatoyannopoulos JA, Lettre G, Orkin SH