MENU

Publications

Journal Article: Cell stem cell Year: 2016
Issue: 1 Volume: 19 Page: 107-19

In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases. 

Biasco L, Pellin D, Scala S, Dionisio F, Basso-Ricci L, Leonardelli L, Scaramuzza S, Baricordi C, Ferrua F, Cicalese MP, Giannelli S, Neduva V, Dow DJ, Schmidt M, Von Kalle C, Roncarolo MG, Ciceri F, Vicard P, Wit E, Di Serio C, Naldini L, Aiuti A
Journal Article: Current gene therapy Year: 2016
Issue: 3 Volume: 16 Page: 184-93

Current Approaches and Future Perspectives for In Vivo Clonal Tracking of Hematopoietic Cells. 

Scala S, Leonardelli L, Biasco L
Journal Article: Science translational medicine Year: 2015
Issue: 317 Volume: 7 Page: 317ra198

Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory. 

Oliveira G, Ruggiero E, Stanghellini MT, Cieri N, D'Agostino M, Fronza R, Lulay C, Dionisio F, Mastaglio S, Greco R, Peccatori J, Aiuti A, Ambrosi A, Biasco L, Bondanza A, Lambiase A, Traversari C, Vago L, von Kalle C, Schmidt M, Bordignon C, Ciceri F, Bonini C
Journal Article: Gene therapy Year: 2015
Issue: 6 Volume: 22 Page: 496-502

Shedding of clinical-grade lentiviral vectors is not detected in a gene therapy setting. 

Cesani M, Plati T, Lorioli L, Benedicenti F, Redaelli D, Dionisio F, Biasco L, Montini E, Naldini L, Biffi A
Journal Article: Science translational medicine Year: 2015
Issue: 273 Volume: 7 Page: 273ra13

In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells. 

Biasco L, Scala S, Basso Ricci L, Dionisio F, Baricordi C, Calabria A, Giannelli S, Cieri N, Barzaghi F, Pajno R, Al-Mousa H, Scarselli A, Cancrini C, Bordignon C, Roncarolo MG, Montini E, Bonini C, Aiuti A
Journal Article: Current gene therapy Year: 2014
Issue: 6 Volume: 14 Page: 429-36

Safety of gene therapy: new insights to a puzzling case. 

Rothe M, Schambach A, Biasco L
Journal Article: Science (New York, N.Y.) Year: 2013
Issue: 6148 Volume: 341 Page: 1233158

Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy. 

Biffi A, Montini E, Lorioli L, Cesani M, Fumagalli F, Plati T, Baldoli C, Martino S, Calabria A, Canale S, Benedicenti F, Vallanti G, Biasco L, Leo S, Kabbara N, Zanetti G, Rizzo WB, Mehta NA, Cicalese MP, Casiraghi M, Boelens JJ, Del Carro U, Dow DJ, Schmidt M, Assanelli A, Neduva V, Di Serio C, Stupka E, Gardner J, von Kalle C, Bordignon C, Ciceri F, Rovelli A, Roncarolo MG, Aiuti A, Sessa M, Naldini L
Journal Article: Science (New York, N.Y.) Year: 2013
Issue: 6148 Volume: 341 Page: 1233151

Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome. 

Aiuti A, Biasco L, Scaramuzza S, Ferrua F, Cicalese MP, Baricordi C, Dionisio F, Calabria A, Giannelli S, Castiello MC, Bosticardo M, Evangelio C, Assanelli A, Casiraghi M, Di Nunzio S, Callegaro L, Benati C, Rizzardi P, Pellin D, Di Serio C, Schmidt M, Von Kalle C, Gardner J, Mehta N, Neduva V, Dow DJ, Galy A, Miniero R, Finocchi A, Metin A, Banerjee PP, Orange JS, Galimberti S, Valsecchi MG, Biffi A, Montini E, Villa A, Ciceri F, Roncarolo MG, Naldini L
Journal Article: Molecular therapy : the journal of the American Society of Gene Therapy Year: 2013
Issue: 1 Volume: 21 Page: 175-84

Preclinical safety and efficacy of human CD34(+) cells transduced with lentiviral vector for the treatment of Wiskott-Aldrich syndrome. 

Scaramuzza S, Biasco L, Ripamonti A, Castiello MC, Loperfido M, Draghici E, Hernandez RJ, Benedicenti F, Radrizzani M, Salomoni M, Ranzani M, Bartholomae CC, Vicenzi E, Finocchi A, Bredius R, Bosticardo M, Schmidt M, von Kalle C, Montini E, Biffi A, Roncarolo MG, Naldini L, Villa A, Aiuti A
Journal Article: Molecular therapy : the journal of the American Society of Gene Therapy Year: 2012
Issue: 4 Volume: 20 Page: 709-16

Retroviral integrations in gene therapy trials. 

Biasco L, Baricordi C, Aiuti A
Journal Article: EMBO molecular medicine Year: 2011
Issue: 2 Volume: 3 Page: 89-101

Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell. 

Biasco L, Ambrosi A, Pellin D, Bartholomae C, Brigida I, Roncarolo MG, Di Serio C, von Kalle C, Schmidt M, Aiuti A
Journal Article: Nature medicine Year: 2009
Issue: 12 Volume: 15 Page: 1431-6

Comprehensive genomic access to vector integration in clinical gene therapy. 

Gabriel R, Eckenberg R, Paruzynski A, Bartholomae CC, Nowrouzi A, Arens A, Howe SJ, Recchia A, Cattoglio C, Wang W, Faber K, Schwarzwaelder K, Kirsten R, Deichmann A, Ball CR, Balaggan KS, Yáñez-Muñoz RJ, Ali RR, Gaspar HB, Biasco L, Aiuti A, Cesana D, Montini E, Naldini L, Cohen-Haguenauer O, Mavilio F, Thrasher AJ, Glimm H, von Kalle C, Saurin W, Schmidt M
Journal Article: The Journal of clinical investigation Year: 2007
Issue: 8 Volume: 117 Page: 2233-40

Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy. 

Aiuti A, Cassani B, Andolfi G, Mirolo M, Biasco L, Recchia A, Urbinati F, Valacca C, Scaramuzza S, Aker M, Slavin S, Cazzola M, Sartori D, Ambrosi A, Di Serio C, Roncarolo MG, Mavilio F, Bordignon C
Journal Article: Blood Year: 2006
Issue: 9 Volume: 108 Page: 2979-88

Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects. 

Mortellaro A, Hernandez RJ, Guerrini MM, Carlucci F, Tabucchi A, Ponzoni M, Sanvito F, Doglioni C, Di Serio C, Biasco L, Follenzi A, Naldini L, Bordignon C, Roncarolo MG, Aiuti A