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Active Grants and Sponsored Research

Sponsor Grant ID: R35 CA210064 Project Date: September 01, 2016 - August 31, 2023
Sponsoring Organization: National Institutes of Health (NIH)

Mechanisms and Vulnerabilities of Aberrant Transcriptional Enhancers in Cancer

Description of Major Goals
The long-term goal of this Outstanding Investigator Award application is to experimentally dissect the specific DNA sequences, transcription factors, transcriptional adaptors and mediators, and epigenetic readers, writers and erasers that are required to form and sustain aberrant transcriptional enhancers capable of driving high levels of key oncogene expression in human cancer cells.
Sponsor Grant ID: R01 CA180692 Project Date: April 01, 2015 - March 31, 2020
Sponsoring Organization: National Institutes of Health (NIH)

Role of LMO1 in Neuroblastoma Initiation and Maintenance

Description of Major Goals
The major goals of this project are to define the regulatory mechanisms of the LMO1 gene and its role in the initiation of neuroblastoma, and to elucidate the mechanisms by which LMO1 contributes to maintenance of the malignant phenotype in neuroblastoma.