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Publications

Journal Article: Arteriosclerosis, thrombosis, and vascular biology Year: 2016
Issue: 3 Volume: 36 Page: 501-9

Synergistic Inhibition of Both P2Y1 and P2Y12 Adenosine Diphosphate Receptors As Novel Approach to Rapidly Attenuate Platelet-Mediated Thrombosis. 

Gremmel T, Yanachkov IB, Yanachkova MI, Wright GE, Wider J, Undyala VV, Michelson A, Frelinger, 3rd AL, Przyklenk K
Journal Article: Seminars in thrombosis and hemostasis Year: 2016

Platelet Physiology. 

Gremmel T, Frelinger, 3rd AL, Michelson A
Journal Article: PloS one Year: 2016
Issue: 8 Volume: 11 Page: e0160933

Modification of Pulsed Electric Field Conditions Results in Distinct Activation Profiles of Platelet-Rich Plasma. 

Frelinger, 3rd AL, Gerrits AJ, Garner AL, Torres AS, Caiafa A, Morton CA, Berny-Lang MA, Carmichael SL, Neculaes VB, Michelson A
Journal Article: European journal of medicinal chemistry Year: 2016
Volume: 107 Page: 204-18

New highly active antiplatelet agents with dual specificity for platelet P2Y1 and P2Y12 adenosine diphosphate receptors. 

Yanachkov IB, Chang H, Yanachkova MI, Dix EJ, Berny-Lang MA, Gremmel T, Michelson A, Wright GE, Frelinger, 3rd AL
Journal Article: Platelets Year: 2015
Page: 1-9

In Vivo and protease-activated receptor-1-mediated platelet activation in patients presenting for cardiac catheterization. 

Gremmel T, Michelson A, Frelinger, 3rd AL
Journal Article: Blood Year: 2015
Issue: 11 Volume: 126 Page: 1367-78

Effects of eltrombopag on platelet count and platelet activation in Wiskott-Aldrich syndrome/X-linked thrombocytopenia. 

Gerrits AJ, Leven EA, Frelinger, 3rd AL, Brigstocke SL, Berny-Lang MA, Mitchell WB, Revel-Vilk S, Tamary H, Carmichael SL, Barnard MR, Michelson A, Bussel JB
Journal Article: Platelets Year: 2015
Page: 1-8

Platelet-rich plasma stimulated by pulse electric fields: Platelet activation, procoagulant markers, growth factor release and cell proliferation. 

Frelinger, Iii AL, Torres AS, Caiafa A, Morton CA, Berny-Lang MA, Gerrits AJ, Carmichael SL, Neculaes VB, Michelson A
Journal Article: Platelets Year: 2015
Page: 1-7

Aspirin response: Differences in serum thromboxane B2 levels between clinical studies. 

Brun C, Daali Y, Combescure C, Zufferey A, Michelson A, Fontana P, Reny JL, Frelinger, 3rd AL
Journal Article: Blood Year: 2015
Issue: 7 Volume: 126 Page: 873-9

Platelet function tests, independent of platelet count, are associated with bleeding severity in ITP. 

Frelinger, 3rd AL, Grace R, Gerrits AJ, Berny-Lang MA, Brown T, Carmichael SL, Neufeld E, Michelson A
Journal Article: Blood Year: 2015

Platelet geometry sensing spatially regulates α-granule secretion to enable matrix self-deposition

Sakurai Y, Fitch-Tewfik J, Qiu Y, Ahn B, Myers D, Tran R, Fay M, Ding L, Spearman P, Michelson A, Flaumenhaft R, Lam W
Journal Article: Platelets

Platelet-rich plasma stimulated by pulse electric fields: Platelet mactivation, procoagulant markers, growth factor release and cell proliferation

Frelinger AL, Tprres AS, Caiafa A, Morton CA, Berny-Lang MA, Gerrits A, Carmichael S, Neculaes VB, Michelson A
Journal Article: Circulation Year: 2014
Issue: 14 Volume: 130 Page: 1192-203

Challenges and priorities for research: a report from the National Heart, Lung, and Blood Institute (NHLBI)/National Institutes of Health (NIH) Working Group on thrombosis in pediatric cardiology and congenital heart disease. 

McCrindle BW, Li JS, Manlhiot C, Tweddell JS, Giglia TM, Massicotte MP, Monagle P, Krishnamurthy R, Mahaffey KW, Michelson A, Verdun N, Almond CS, Newburger JW, Brandão LR, Esmon CT, Manco-Johnson MJ, Ichord R, Ortel TL, Chan AK, Portman R, Rose M, Strony J, Kaltman JR
Journal Article: The journal of trauma and acute care surgery Year: 2014
Issue: 3 Suppl 2 Volume: 77 Page: S94-S100

Platelet activation using electric pulse stimulation: growth factor profile and clinical implications. 

Torres AS, Caiafa A, Garner AL, Klopman S, LaPlante N, Morton C, Conway K, Michelson A, Frelinger, 3rd AL, Neculaes VB
Journal Article: Journal of the American College of Cardiology Year: 2014
Issue: 4 Volume: 64 Page: 361-8

Variability of individual platelet reactivity over time in patients treated with clopidogrel: insights from the ELEVATE-TIMI 56 trial. 

Hochholzer W, Ruff CT, Mesa RA, Mattimore JF, Cyr JF, Lei L, Frelinger, 3rd AL, Michelson A, Berg DD, Angiolillo DJ, O'Donoghue ML, Sabatine MS, Mega JL
Journal Article: International journal of laboratory hematology Year: 2014
Volume: 37 Page: 112-119

Do immature platelet levels in chest pain patients presenting to the emergency department aid in the diagnosis of acute coronary syndrome? 

Berny-Lang MA, Darling CE, Frelinger, 3rd AL, Barnard MR, Smith CS, Michelson A
Journal Article: BMJ open Year: 2014
Issue: 1 Volume: 4 Page: e003883

Point-of-care assessment of platelet reactivity in the emergency department may facilitate rapid rule-out of acute coronary syndromes: a prospective cohort pilot feasibility study. 

Darling CE, Sala Mercado JA, Quiroga-Castro W, Tecco GF, Zelaya FR, Conci EC, Sala JP, Smith CS, Michelson A, Whittaker P, Welch RD, Przyklenk K
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2014
Issue: 1 Volume: 12 Page: 2-13

Clinical implications of drug-drug interactions with P2Y12 receptor inhibitors. 

Siller-Matula JM, Trenk D, Krähenbühl S, Michelson A, Delle-Karth G
Journal Article: Platelets Year: 2014
Issue: 1 Volume: 25 Page: 27-35

Platelet activation and inhibition in sickle cell disease (pains) study. 

Frelinger, 3rd AL, Jakubowski JA, Brooks JK, Carmichael SL, Berny-Lang MA, Barnard MR, Heeney M, Michelson A
Journal Article: Blood Year: 2013
Issue: 3 Volume: 122 Page: 376-85

The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation. 

Smith BW, Rozelle SS, Leung A, Ubellacker J, Parks A, Nah SK, French D, Gadue P, Monti S, Chui DH, Steinberg MH, Frelinger A, Michelson A, Theberge R, McComb ME, Costello CE, Kotton DN, Mostoslavsky G, Sherr DH, Murphy GJ
Journal Article: Journal of the American Heart Association Year: 2013
Issue: 3 Volume: 2 Page: e000026

P2Y12 receptor blockade augments glycoprotein IIb-IIIa antagonist inhibition of platelet activation, aggregation, and procoagulant activity. 

Berny-Lang MA, Jakubowski JA, Sugidachi A, Barnard MR, Michelson A, Frelinger, 3rd AL
Letter (to Editor/Journal): Journal of thrombosis and haemostasis : JTH Year: 2013
Issue: 5 Volume: 11 Page: 1002-3

Differences in platelet function in patients with acute myeloid leukemia and myelodysplasia compared to equally thrombocytopenic patients with immune thrombocytopenia: a reply to a rebuttal. 

Psaila B, Bussel JB, Frelinger A, Michelson A
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2013

Recommendations for the Standardization of Light Transmission Aggregometry: A Consensus of the Working Party from the Platelet Physiology Subcommittee of SSC/ISTH. 

Cattaneo M, Cerletti C, Harrison P, Hayward CP, Kenny D, Nugent D, Nurden P, Rao AK, Schmaier AH, Watson SP, Lussana F, Pugliano MT, Michelson A
Journal Article: Journal of the American College of Cardiology Year: 2013
Issue: 8 Volume: 61 Page: 872-9

Clopidogrel pharmacokinetics and pharmacodynamics vary widely despite exclusion or control of polymorphisms (CYP2C19, ABCB1, PON1), noncompliance, diet, smoking, co-medications (including proton pump inhibitors), and pre-existent variability in platelet function. 

Frelinger, 3rd AL, Bhatt DL, Lee RD, Mulford DJ, Wu J, Nudurupati S, Nigam A, Lampa M, Brooks JK, Barnard MR, Michelson A
Journal Article: Blood Year: 2013
Issue: 2 Volume: 121 Page: 250

Gray platelet syndrome. 

Michelson A
Journal Article: Acta haematologica Year: 2013
Issue: 3 Volume: 130 Page: 181-7

Clinical and laboratory significance of defective P2Y(12) pathway function in patients with myeloproliferative neoplasms: a pilot study. 

Chang H, Shih LY, Michelson A, Dunn P, Frelinger A, Wang PN, Kuo MC, Lin TL, Wu J, Tang TC
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2012
Issue: 12 Volume: 10 Page: 2573-80

Modified diadenosine tetraphosphates with dual specificity for P2Y1 and P2Y12 are potent antagonists of ADP-induced platelet activation. 

Chang H, Yanachkov IB, Dix EJ, Li YF, Barnard MR, Wright GE, Michelson A, Frelinger, 3rd AL
Conference Proceeding: Circulation Year: 2012
Issue: 13 Volume: 126 Page: 1645-62

Guided antithrombotic therapy: current status and future research direction: report on a National Heart, Lung and Blood Institute working group. 

Fuster V, Bhatt DL, Califf RM, Michelson A, Sabatine MS, Angiolillo DJ, Bates ER, Cohen DJ, Coller BS, Furie B, Hulot JS, Mann KG, Mega JL, Musunuru K, O'Donnell CJ, Price MJ, Schneider DJ, Simon DI, Weitz JI, Williams MS, Hoots WK, Rosenberg YD, Hasan AA
Journal Article: Blood Year: 2012
Issue: 1 Volume: 120 Page: 199-206

Granule exocytosis is required for platelet spreading: differential sorting of α-granules expressing VAMP-7. 

Peters CG, Michelson A, Flaumenhaft R
Journal Article: Blood Year: 2012
Issue: 17 Volume: 119 Page: 4066-72

In vivo effects of eltrombopag on platelet function in immune thrombocytopenia: no evidence of platelet activation. 

Psaila B, Bussel JB, Linden MD, Babula B, Li Y, Barnard MR, Tate C, Mathur K, Frelinger A, Michelson A
Journal Article: Journal of the American College of Cardiology Year: 2012
Issue: 14 Volume: 59 Page: 1304-11

A randomized, 2-period, crossover design study to assess the effects of dexlansoprazole, lansoprazole, esomeprazole, and omeprazole on the steady-state pharmacokinetics and pharmacodynamics of clopidogrel in healthy volunteers. 

Frelinger, 3rd AL, Lee RD, Mulford DJ, Wu J, Nudurupati S, Nigam A, Brooks JK, Bhatt DL, Michelson A
Journal Article: Platelets Year: 2012
Issue: 6 Volume: 23 Page: 430-8

Pharmacodynamic effects of clopidogrel in pediatric cardiac patients: a comparative study of platelet aggregation response. 

Jennings LK, Michelson A, Jacoski MV, Tyagi A, Grgurevich S, Li JS, Picolo Investigators
Journal Article: JAMA Year: 2011
Issue: 20 Volume: 306 Page: 2221-8

Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease. 

Mega JL, Hochholzer W, Frelinger, 3rd AL, Kluk MJ, Angiolillo DJ, Kereiakes DJ, Isserman S, Rogers WJ, Ruff CT, Contant C, Pencina MJ, Scirica BM, Longtine JA, Michelson A, Sabatine MS
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2011
Issue: 11 Volume: 9 Page: 2302-10

Differences in platelet function in patients with acute myeloid leukemia and myelodysplasia compared to equally thrombocytopenic patients with immune thrombocytopenia. 

Psaila B, Bussel JB, Frelinger A, Babula B, Linden MD, Li Y, Barnard MR, Tate C, Feldman EJ, Michelson A
Journal Article: Thrombosis and haemostasis Year: 2011
Issue: 2 Volume: 106 Page: 219-26

Intrinsic platelet reactivity before P2Y12 blockade contributes to residual platelet reactivity despite high-level P2Y12 blockade by prasugrel or high-dose clopidogrel. Results from PRINCIPLE-TIMI 44. 

Frelinger, 3rd AL, Michelson A, Wiviott SD, Trenk D, Neumann FJ, Miller D, Jakubowski JA, Costigan TM, McCabe CH, Antman EM, Braunwald E
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2011
Issue: 5 Volume: 9 Page: 1020-8

Effects of in vitro adult platelet transfusions on neonatal hemostasis. 

Ferrer-Marin F, Chavda C, Lampa M, Michelson A, Frelinger, 3rd AL, Sola-Visner M
Journal Article: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine Year: 2011
Issue: 2 Volume: 7 Page: 172-8

The influence of intermittent hypoxemia on platelet activation in obese patients with obstructive sleep apnea. 

Rahangdale S, Yeh SY, Novack V, Stevenson K, Barnard MR, Furman MI, Frelinger A, Michelson A, Malhotra A
Journal Article: European heart journal Year: 2011
Issue: 7 Volume: 32 Page: 838-46

A pharmacodynamic comparison of prasugrel vs. high-dose clopidogrel in patients with type 2 diabetes mellitus and coronary artery disease: results of the Optimizing anti-Platelet Therapy In diabetes MellitUS (OPTIMUS)-3 Trial. 

Angiolillo DJ, Badimon JJ, Saucedo JF, Frelinger A, Michelson A, Jakubowski JA, Zhu B, Ojeh CK, Baker BA, Effron MB
Journal Article: Pediatrics Year: 2011
Issue: 2 Volume: 127 Page: 347-57

Hormonal contraception and thrombotic risk: a multidisciplinary approach. 

Trenor, 3rd CC, Chung RJ, Michelson A, Neufeld E, Gordon CM, Laufer MR, Emans J
Journal Article: Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program Year: 2011
Volume: 2011 Page: 62-9

Advances in antiplatelet therapy. 

Michelson A
Journal Article: PloS one Year: 2011
Issue: 9 Volume: 6 Page: e24549

The human endogenous circadian system causes greatest platelet activation during the biological morning independent of behaviors. 

Scheer FA, Michelson A, Frelinger, 3rd AL, Evoniuk H, Kelly EE, McCarthy M, Doamekpor LA, Barnard MR, Shea SA
Journal Article: Circulation. Cardiovascular interventions Year: 2010
Issue: 5 Volume: 3 Page: 442-9

The Platelet Activity After Clopidogrel Termination (PACT) study. 

Frelinger, 3rd AL, Barnard MR, Fox ML, Michelson A
Other: Circulation Year: 2010
Issue: 16 Volume: 121 Page: 1795-7

Thrombophilia and pediatric stroke. 

Trenor, 3rd CC, Michelson A
Journal Article: Thrombosis research Year: 2010
Issue: 2 Volume: 125 Page: 159-65

Agonist and antagonist effects of diadenosine tetraphosphate, a platelet dense granule constituent, on platelet P2Y1, P2Y12 and P2X1 receptors. 

Chang H, Yanachkov IB, Michelson A, Li Y, Barnard MR, Wright GE, Frelinger, 3rd AL
Journal Article: Nature reviews. Drug discovery Year: 2010
Issue: 2 Volume: 9 Page: 154-69

Antiplatelet therapies for the treatment of cardiovascular disease. 

Michelson A
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2010
Issue: 2 Volume: 8 Page: 331-40

Targeted inhibition of the serotonin 5HT2A receptor improves coronary patency in an in vivo model of recurrent thrombosis. 

Przyklenk K, Frelinger, 3rd AL, Linden MD, Whittaker P, Li Y, Barnard MR, Adams J, Morgan M, Al-Shamma H, Michelson A
Journal Article: Platelets Year: 2010
Issue: 7 Volume: 21 Page: 525-32

Soluble CD40 ligand is elevated in type 1 diabetic nephropathy but not predictive of mortality, cardiovascular events or kidney function. 

Lajer M, Tarnow I, Michelson A, Jorsal A, Frelinger A, Parving HH, Rossing P, Tarnow L
Journal Article: Circulation Year: 2009
Issue: 25 Volume: 120 Page: 2586-96

Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization. 

Frelinger, 3rd AL, Li Y, Linden MD, Barnard MR, Fox ML, Christie DJ, Furman MI, Michelson A
Journal Article: Platelets Year: 2009
Issue: 7 Volume: 20 Page: 513-9

Nephropathy in type 1 diabetes is associated with increased circulating activated platelets and platelet hyperreactivity. 

Tarnow I, Michelson A, Barnard MR, Frelinger, 3rd AL, Aasted B, Jensen BR, Parving HH, Rossing P, Tarnow L
Journal Article: Lancet (London, England) Year: 2009
Issue: 9694 Volume: 374 Page: 989-97

Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials. 

O'Donoghue ML, Braunwald E, Antman EM, Murphy SA, Bates ER, Rozenman Y, Michelson A, Hautvast RW, Ver Lee PN, Close SL, Shen L, Mega JL, Sabatine MS, Wiviott SD
Journal Article: Current opinion in hematology Year: 2009
Issue: 5 Volume: 16 Page: 371-7

New P2Y12 antagonists. 

Michelson A
Journal Article: European heart journal Year: 2009
Issue: 14 Volume: 30 Page: 1753-63

Pharmacodynamic assessment of platelet inhibition by prasugrel vs. clopidogrel in the TRITON-TIMI 38 trial. 

Michelson A, Frelinger, 3rd AL, Braunwald E, Downey WE, Angiolillo DJ, Xenopoulos NP, Jakubowski JA, Li Y, Murphy SA, Qin J, McCabe CH, Antman EM, Wiviott SD
Journal Article: Journal of thrombosis and thrombolysis Year: 2009
Issue: 1 Volume: 28 Page: 31-7

Platelet reactivity and the identification of acute coronary syndromes in the emergency department. 

Darling CE, Michelson A, Volturo GA, Przyklenk K
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2009
Issue: 6 Volume: 7 Page: 1029

Results of a worldwide survey on the assessment of platelet function by light transmission aggregometry: a report from the platelet physiology subcommittee of the SSC of the ISTH. 

Cattaneo M, Hayward CP, Moffat KA, Pugliano MT, Liu Y, Michelson A
Journal Article: Thrombosis research Year: 2009
Issue: 1 Volume: 124 Page: 42-5

The platelet hyporeactivity of extremely low birth weight neonates is age-dependent. 

Bednarek FJ, Bean S, Barnard MR, Frelinger A, Michelson A
Journal Article: The American journal of cardiology Year: 2009
Issue: 3 Suppl Volume: 103 Page: 20A-26A

Methods for the measurement of platelet function. 

Michelson A
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2008
Issue: 12 Volume: 6 Page: 2035-44

Aspirin 'resistance': role of pre-existent platelet reactivity and correlation between tests. 

Frelinger A, Li Y, Linden MD, Tarnow I, Barnard MR, Fox ML, Michelson A
Journal Article: Infection and immunity Year: 2008
Issue: 12 Volume: 76 Page: 5706-13

Platelet antistaphylococcal responses occur through P2X1 and P2Y12 receptor-induced activation and kinocidin release. 

Trier DA, Gank KD, Kupferwasser D, Yount NY, French WJ, Michelson A, Kupferwasser LI, Xiong YQ, Bayer AS, Yeaman MR
Journal Article: Veterinary immunology and immunopathology Year: 2008
Issue: 3-4 Volume: 123 Page: 345-52

Effects of physiologic agonists on canine whole blood flow cytometry assays of leukocyte-platelet aggregation and platelet activation. 

Tarnow I, Kristensen AT, Krogh AK, Frelinger, 3rd AL, Barnard MR, Michelson A
Journal Article: Chest Year: 2008
Issue: 6 Suppl Volume: 133 Page: 887S-968S

Antithrombotic therapy in neonates and children: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). 

Monagle P, Chalmers E, Chan A, DeVeber G, Kirkham F, Massicotte P, Michelson A
Journal Article: Clinical cardiology Year: 2008
Issue: 3 Suppl 1 Volume: 31 Page: I2-9

Antiplatelet strategies: evaluating their current role in the setting of acute coronary syndromes. 

Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson A, Peterson E, Wiviott S
Journal Article: Clinical cardiology Year: 2008
Issue: 3 Suppl 1 Volume: 31 Page: I36

Antiplatelet therapy and platelet function testing. 

Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson A, Peterson E, Wiviott S
Other: Clinical cardiology Year: 2008
Issue: 3 Suppl 1 Volume: 31 Page: I1

Antiplatelet therapy and platelet function testing. Introduction. 

Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson A, Peterson E, Wiviott S
Journal Article: Clinical cardiology Year: 2008
Issue: 3 Suppl 1 Volume: 31 Page: I10-6

Assessing the current role of platelet function testing. 

Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson A, Peterson E, Wiviott S
Journal Article: Clinical cardiology Year: 2008
Issue: 3 Suppl 1 Volume: 31 Page: I28-35

Clinical considerations with the use of antiplatelet therapy in patients undergoing percutaneous coronary intervention. 

Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson A, Peterson E, Wiviott S
Journal Article: Clinical cardiology Year: 2008
Issue: 3 Suppl 1 Volume: 31 Page: I21-7

Investigating the mechanisms of hyporesponse to antiplatelet approaches. 

Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson A, Peterson E, Wiviott S
Journal Article: Arteriosclerosis, thrombosis, and vascular biology Year: 2008
Issue: 3 Volume: 28 Page: s33-8

P2Y12 antagonism: promises and challenges. 

Michelson A
Journal Article: Clinical cardiology Year: 2008
Issue: 3 Suppl 1 Volume: 31 Page: I17-20

The problem of persistent platelet activation in acute coronary syndromes and following percutaneous coronary intervention. 

Braunwald E, Angiolillo D, Bates E, Berger PB, Bhatt D, Cannon CP, Furman MI, Gurbel P, Michelson A, Peterson E, Wiviott S
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2008
Issue: 2 Volume: 6 Page: 359-65

The active metabolite of prasugrel inhibits adenosine diphosphate- and collagen-stimulated platelet procoagulant activities. 

Frelinger, 3rd AL, Jakubowski JA, Li Y, Barnard MR, Linden MD, Tarnow I, Fox ML, Sugidachi A, Winters KJ, Furman MI, Michelson A
Journal Article: Circulation Year: 2008
Issue: 4 Volume: 117 Page: 553-9

Dosing of clopidogrel for platelet inhibition in infants and young children: primary results of the Platelet Inhibition in Children On cLOpidogrel (PICOLO) trial. 

Li JS, Yow E, Berezny KY, Bokesch PM, Takahashi M, Graham, Jr TP, Sanders SP, Sidi D, Bonnet D, Ewert P, Jennings LK, Michelson A
Journal Article: Thrombosis research Year: 2008
Issue: 5 Volume: 121 Page: 689-98

Effect of adenosine A2 receptor stimulation on platelet activation-aggregation: differences between canine and human models. 

Linden MD, Barnard MR, Frelinger A, Michelson A, Przyklenk K
Journal Article: Circulation Year: 2007
Issue: 25 Volume: 116 Page: 2923-32

Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial. 

Wiviott SD, Trenk D, Frelinger A, O'Donoghue M, Neumann FJ, Michelson A, Angiolillo DJ, Hod H, Montalescot G, Miller D, Jakubowski JA, Cairns R, Murphy SA, McCabe CH, Antman EM, Braunwald E
Journal Article: Journal of the American College of Cardiology Year: 2007
Issue: 19 Volume: 50 Page: 1822-34

Platelet function monitoring in patients with coronary artery disease. 

Gurbel PA, Becker R, Mann KG, Steinhubl SR, Michelson A
Journal Article: Thrombosis and haemostasis Year: 2007
Issue: 1 Volume: 98 Page: 192-200

The active metabolite of prasugrel inhibits ADP-stimulated thrombo-inflammatory markers of platelet activation: Influence of other blood cells, calcium, and aspirin. 

Frelinger, 3rd AL, Jakubowski JA, Li Y, Barnard MR, Fox ML, Linden MD, Sugidachi A, Winters KJ, Furman MI, Michelson A
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2007
Issue: 4 Volume: 5 Page: 761-5

Indices of platelet activation and the stability of coronary artery disease. 

Linden MD, Furman MI, Frelinger, 3rd AL, Fox ML, Barnard MR, Li Y, Przyklenk K, Michelson A
Journal Article: Thrombosis research Year: 2007
Issue: 2 Volume: 121 Page: 159-62

Cystic fibrosis heterozygotes do not have increased platelet activation. 

Tarnow I, Michelson A, Frelinger, 3rd AL, Linden MD, Li Y, Fox ML, Barnard MR, O'Sullivan BP
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2007
Issue: 1 Volume: 5 Page: 75-81

Evidence that pre-existent variability in platelet response to ADP accounts for 'clopidogrel resistance'. 

Michelson A, Linden MD, Furman MI, Li Y, Barnard MR, Fox ML, Lau WC, McLaughlin TJ, Frelinger A
Journal Article: Thrombosis research Year: 2007
Issue: 3 Volume: 120 Page: 323-36

Measuring antiplatelet drug effects in the laboratory. 

Harrison P, Frelinger, 3rd AL, Furman MI, Michelson A
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2006
Issue: 12 Volume: 4 Page: 2670-7

Preconditioning ischemia attenuates molecular indices of platelet activation-aggregation. 

Linden MD, Whittaker P, Frelinger, 3rd AL, Barnard MR, Michelson A, Przyklenk K
Journal Article: The American journal of cardiology Year: 2006
Issue: 10A Volume: 98 Page: 4N-10N

Current options in platelet function testing. 

Michelson A, Frelinger, 3rd AL, Furman MI
Other: Circulation Year: 2006
Issue: 20 Volume: 114 Page: 2094-5

Arterial ischemic stroke in children: baby steps. 

Michelson A
Journal Article: Reviews in cardiovascular medicine Year: 2006
Issue: 4 Volume: 7 Page: 214-25

Therapeutic goals for effective platelet inhibition: a consensus document. 

Wiviott SD, Michelson A, Berger PB, Lepor NE, Kereiakes DJ
Journal Article: The American journal of cardiology Year: 2006
Issue: 5 Volume: 98 Page: 577-9

Frequency of aspirin resistance in a community hospital. 

Mirkhel A, Peyster E, Sundeen J, Greene L, Michelson A, Hasan A, Domanski M
Journal Article: Circulation Year: 2006
Issue: 25 Volume: 113 Page: 2888-96

Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance. 

Frelinger, 3rd AL, Furman MI, Linden MD, Li Y, Fox ML, Barnard MR, Michelson A
Journal Article: Reviews in cardiovascular medicine Year: 2006
Issue: 2 Volume: 7 Page: 75-81

Platelet activation and progression to complications. 

Kereiakes DJ, Michelson A
Journal Article: American journal of respiratory and critical care medicine Year: 2006
Issue: 5 Volume: 173 Page: 483-90

The inflammatory role of platelets in cystic fibrosis. 

O'Sullivan BP, Michelson A
Journal Article: Thrombosis research Year: 2006
Issue: 1 Volume: 118 Page: 75-83

Antiplatelet therapy in children. 

Israels SJ, Michelson A
Journal Article: Pathophysiology of haemostasis and thrombosis Year: 2006
Issue: 1-2 Volume: 35 Page: 5-9

Aspirin resistance. 

Michelson A
Journal Article: Pathophysiology of haemostasis and thrombosis Year: 2006
Issue: 1-2 Volume: 35 Page: 67-82

Evaluation of platelet function by flow cytometry. 

Michelson A
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2005
Issue: 11 Volume: 3 Page: 2563-70

Effects of platelet binding on whole blood flow cytometry assays of monocyte and neutrophil procoagulant activity. 

Barnard MR, Linden MD, Frelinger, 3rd AL, Li Y, Fox ML, Furman MI, Michelson A
Journal Article: American heart journal Year: 2005
Issue: 5 Volume: 150 Page: 882-6

Noncompliance in cardiovascular clinical trials. 

Serebruany VL, Oshrine BR, Malinin AI, Atar D, Michelson A, Ferguson, 3rd JJ
Other: Journal of the American College of Cardiology Year: 2005
Issue: 4 Volume: 46 Page: 646-7

Clopidogrel linking evaluation of platelet response variability to mechanism of action. 

Frelinger, 3rd AL, Michelson A
Conference Proceeding: MedGenMed : Medscape general medicine Year: 2005
Issue: 3 Volume: 7 Page: 76

Aspirin resistance and its implications in clinical practice. 

Eikelboom J, Feldman M, Mehta S, Michelson A, Oates JA, Topol E
Journal Article: Blood Year: 2005
Issue: 12 Volume: 105 Page: 4635-41

Platelet activation in cystic fibrosis. 

O'Sullivan BP, Linden MD, Frelinger, 3rd AL, Barnard MR, Spencer-Manzon M, Morris JE, Salem RO, Laposata M, Michelson A
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2005
Issue: 6 Volume: 3 Page: 1309-11

Aspirin resistance: position paper of the Working Group on Aspirin Resistance. 

Michelson A, Cattaneo M, Eikelboom JW, Gurbel P, Kottke-Marchant K, Kunicki TJ, Pulcinelli FM, Cerletti C, Rao AK
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2005
Issue: 2 Volume: 3 Page: 312-20

GPIIb-IIIa antagonists reduce thromboinflammatory processes in patients with acute coronary syndromes undergoing percutaneous coronary intervention. 

Furman MI, Krueger LA, Linden MD, Fox ML, Ball SP, Barnard MR, Frelinger, 3rd AL, Michelson A
Journal Article: Vox sanguinis Year: 2005
Issue: 2 Volume: 88 Page: 122-9

Survival of baboon biotin-X-N-hydroxysuccinimide and (111)In-oxine-labelled autologous fresh and lyophilized reconstituted platelets. 

Valeri CR, MacGregor H, Barnard MR, Summaria L, Michelson A, Ragno G
Journal Article: Hematology (Amsterdam, Netherlands) Year: 2005
Volume: 10 Suppl 1 Page: 132-7

Platelet function testing in cardiovascular diseases. 

Michelson A
Journal Article: Circulation Year: 2004
Issue: 19 Volume: 110 Page: e489-93

Platelet function testing in cardiovascular diseases. 

Michelson A
Journal Article: Seminars in thrombosis and hemostasis Year: 2004
Issue: 5 Volume: 30 Page: 501-11

Application of flow cytometry to platelet disorders. 

Linden MD, Frelinger, 3rd AL, Barnard MR, Przyklenk K, Furman MI, Michelson A
Journal Article: Transfusion Year: 2004
Issue: 10 Volume: 44 Page: 1505-12

In vitro testing of fresh and lyophilized reconstituted human and baboon platelets. 

Valeri CR, Macgregor H, Barnard MR, Summaria L, Michelson A, Ragno G
Journal Article: Chest Year: 2004
Issue: 3 Suppl Volume: 126 Page: 645S-687S

Antithrombotic therapy in children: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. 

Monagle P, Chan A, Massicotte P, Chalmers E, Michelson A
Journal Article: Journal of thrombosis and thrombolysis Year: 2004
Issue: 1 Volume: 18 Page: 11-7

GPIIb/IIIa inhibitor-induced dethrombosis. 

Furman MI, Frelinger, 3rd AL, Michelson A
Journal Article: Journal of the American College of Cardiology Year: 2004
Issue: 12 Volume: 43 Page: 2319-25

Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization. 

Furman MI, Krueger LA, Linden MD, Barnard MR, Frelinger, 3rd AL, Michelson A
Journal Article: The American journal of cardiology Year: 2003
Issue: 9 Volume: 92 Page: 1099-101

Combined effects of mild hypothermia and glycoprotein IIb/IIIa antagonists on platelet-platelet and leukocyte-platelet aggregation. 

Frelinger, 3rd AL, Furman MI, Barnard MR, Krueger LA, Dae MW, Michelson A
Journal Article: Blood Year: 2003
Issue: 8 Volume: 102 Page: 2843-50

Spirochete-platelet attachment and thrombocytopenia in murine relapsing fever borreliosis. 

Alugupalli KR, Michelson A, Joris I, Schwan TG, Hodivala-Dilke K, Hynes RO, Leong JM
Journal Article: Journal of thrombosis and thrombolysis Year: 2003
Issue: 1-2 Volume: 16 Page: 7-12

How platelets work: platelet function and dysfunction. 

Michelson A
Journal Article: Seminars in thrombosis and hemostasis Year: 2003
Issue: 4 Volume: 29 Page: 363-72

Neonatal platelet function. 

Israels SJ, Rand ML, Michelson A
Journal Article: Journal of thrombosis and thrombolysis Year: 2003
Issue: 1-2 Volume: 16 Page: 13-5

Platelet inhibitor therapy: mechanisms of action and clinical use. 

Michelson A
Journal Article: Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.] Year: 2003
Volume: Chapter 6 Page: Unit 6.15

Whole blood analysis of leukocyte-platelet aggregates. 

Barnard MR, Krueger LA, Frelinger, 3rd AL, Furman MI, Michelson A
Journal Article: Blood Year: 2003
Issue: 6 Volume: 101 Page: 2268-76

Two novel mutations in the alpha IIb calcium-binding domains identify hydrophobic regions essential for alpha IIbbeta 3 biogenesis. 

Mitchell WB, Li JH, Singh F, Michelson A, Bussel J, Coller BS, French DL
Journal Article: Journal of thrombosis and haemostasis : JTH Year: 2003
Issue: 2 Volume: 1 Page: 355-62

Platelet FcgammaRIIA His131Arg polymorphism and platelet function: antibodies to platelet-bound fibrinogen induce platelet activation. 

Chen J, Dong JF, Sun C, Bergeron A, McBride L, Pillai M, Barnard MR, Salmon J, Michelson A, Bray PF
Journal Article: American heart journal Year: 2003
Issue: 2 Volume: 145 Page: e6

Quantification of abciximab-induced platelet inhibition is assay dependent: a comparative study in patients undergoing percutaneous coronary intervention. 

Furman MI, Kereiakes DJ, Krueger LA, Mueller MN, Broderick TM, Schneider JF, Howard WL, Fox ML, Barnard MR, Frelinger, 3rd AL, Michelson A
Journal Article: Journal of vascular surgery Year: 2003
Issue: 2 Volume: 37 Page: 440-5

The cleaved peptide of PAR1 is a more potent stimulant of platelet-endothelial cell adhesion than is thrombin. 

Claytor RB, Michelson A, Li JM, Frelinger, 3rd AL, Rohrer MJ, Garnette CS, Barnard MR, Krueger LA, Furman MI
Journal Article: Cardiovascular surgery (London, England) Year: 2002
Issue: 5 Volume: 10 Page: 464-9

Platelet-monocyte aggregates in patients with chronic venous insufficiency remain elevated following correction of reflux. 

Rohrer MJ, Claytor RB, Garnette CS, Powell CC, Barnard MR, Furman MI, Michelson A
Journal Article: Thrombosis and haemostasis Year: 2002
Issue: 6 Volume: 87 Page: 1020-5

An additional mechanism of action of abciximab: dispersal of newly formed platelet aggregates. 

Marciniak, Jr SJ, Mascelli MA, Furman MI, Michelson A, Jakubowski JA, Jordan RE, Marchese PJ, Frelinger A
Journal Article: American heart journal Year: 2002
Issue: 4 Volume: 143 Page: 602-11

The Ultegra rapid platelet-function assay: comparison to standard platelet function assays in patients undergoing percutaneous coronary intervention with abciximab therapy. 

Wheeler GL, Braden GA, Steinhubl SR, Kereiakes DJ, Kottke-Marchant K, Michelson A, Furman MI, Mueller MN, Moliterno DJ, Sane DC
Journal Article: Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.] Year: 2002
Volume: Chapter 6 Page: Unit 6.10

Immunophenotypic analysis of platelets. 

Krueger LA, Barnard MR, Frelinger, 3rd AL, Furman MI, Michelson A
Journal Article: American heart journal Year: 2001
Issue: 5 Volume: 142 Page: 790-8

Leukocyte-platelet aggregation, platelet surface P-selectin, and platelet surface glycoprotein IIIa after percutaneous coronary intervention: Effects of dalteparin or unfractionated heparin in combination with abciximab. 

Furman MI, Kereiakes DJ, Krueger LA, Mueller MN, Pieper K, Broderick TM, Schneider JF, Howard WL, Fox ML, Barnard MR, Frelinger, 3rd AL, Michelson A
Journal Article: Journal of the American College of Cardiology Year: 2001
Issue: 4 Volume: 38 Page: 1002-6

Circulating monocyte-platelet aggregates are an early marker of acute myocardial infarction. 

Furman MI, Barnard MR, Krueger LA, Fox ML, Shilale EA, Lessard DM, Marchese P, Frelinger, 3rd AL, Goldberg RJ, Michelson A
Journal Article: Circulation Year: 2001
Issue: 12 Volume: 104 Page: 1374-9

Dissociation of glycoprotein IIb/IIIa antagonists from platelets does not result in fibrinogen binding or platelet aggregation. 

Frelinger, 3rd AL, Furman MI, Krueger LA, Barnard MR, Michelson A
Journal Article: Blood Year: 2001
Issue: 5 Volume: 98 Page: 1440-7

Regulation of P-selectin binding to the neutrophil P-selectin counter-receptor P-selectin glycoprotein ligand-1 by neutrophil elastase and cathepsin G. 

Gardiner EE, De Luca M, McNally T, Michelson A, Andrews RK, Berndt MC
Journal Article: Thrombosis and haemostasis Year: 2001
Issue: 2 Volume: 86 Page: 668-71

Serial determinations of platelet counts in mice by flow cytometry. 

Alugupalli KR, Michelson A, Barnard MR, Leong JM
Journal Article: Cytometry Year: 2001
Issue: 4 Volume: 43 Page: 308-13

Laser scanning cytometry: a novel method for the detection of platelet--endothelial cell adhesion. 

Claytor RB, Li JM, Furman MI, Garnette CS, Rohrer MJ, Barnard MR, Krueger LA, Frelinger, 3rd AL, Michelson A
Journal Article: Chest Year: 2001
Issue: 1 Suppl Volume: 119 Page: 344S-370S

Antithrombotic therapy in children. 

Monagle P, Michelson A, Bovill E, Andrew M
Journal Article: Molecular microbiology Year: 2001
Issue: 2 Volume: 39 Page: 330-40

Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin alphaIIbbeta3 activation. 

Alugupalli KR, Michelson A, Barnard MR, Robbins D, Coburn J, Baker EK, Ginsberg MH, Schwan TG, Leong JM
Journal Article: Thrombosis and haemostasis Year: 2000
Issue: 5 Volume: 84 Page: 897-903

The cleaved peptide of PAR1 results in a redistribution of the platelet surface GPIb-IX-V complex to the surface-connected canalicular system. 

Furman MI, Nurden P, Berndt MC, Nurden AT, Benoit SE, Barnard MR, Ofosu FA, Michelson A
Journal Article: Thrombosis and haemostasis Year: 2000
Issue: 4 Volume: 84 Page: 689-94

Platelet and platelet-derived microparticle surface factor V/Va binding in whole blood: differences between neonates and adults. 

Michelson A, Rajasekhar D, Bednarek FJ, Barnard MR
Journal Article: Current cardiology reports Year: 2000
Issue: 5 Volume: 2 Page: 386-94

Antithrombotic therapy in the cardiac catheterization laboratory: focus on antiplatelet agents. 

Furman MI, Frelinger III AL, Michelson A
Journal Article: Thrombosis and haemostasis Year: 2000
Issue: 3 Volume: 84 Page: 492-8

GPIIb-IIIa antagonist-induced reduction in platelet surface factor V/Va binding and phosphatidylserine expression in whole blood. 

Furman MI, Krueger LA, Frelinger, 3rd AL, Barnard MR, Mascelli MA, Nakada MT, Michelson A
Journal Article: Methods (San Diego, Calif.) Year: 2000
Issue: 3 Volume: 21 Page: 259-70

Evaluation of platelet function by flow cytometry. 

Michelson A, Barnard MR, Krueger LA, Frelinger, 3rd AL, Furman MI
Journal Article: Circulation Year: 2000
Issue: 9 Volume: 101 Page: 1013-8

Platelet GP IIIa Pl(A) polymorphisms display different sensitivities to agonists. 

Michelson A, Furman MI, Goldschmidt-Clermont P, Mascelli MA, Hendrix C, Coleman L, Hamlington J, Barnard MR, Kickler T, Christie DJ, Kundu S, Bray PF
Journal Article: Vox sanguinis Year: 2000
Volume: 78 Suppl 2 Page: 137-42

Flow cytometric analysis of platelets. 

Michelson A
Journal Article: Transactions of the American Clinical and Climatological Association Year: 2000
Volume: 111 Page: 158-63

Nitric oxide insufficiency and arterial thrombosis. 

Loscalzo J, Freedman J, Inbal A, Keaney, Jr JF, Michelson A, Vita JA
Journal Article: Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program Year: 2000
Page: 222-240

Platelets: New Understanding of Platelet Glycoproteins and Their Role in Disease. 

Bussel JB, Kunicki TJ, Michelson A
Journal Article: Journal of vascular surgery Year: 1999
Issue: 5 Volume: 30 Page: 844-51

Chronic venous insufficiency is associated with increased platelet and monocyte activation and aggregation. 

Powell CC, Rohrer MJ, Barnard MR, Peyton BD, Furman MI, Michelson A
Journal Article: Current opinion in hematology Year: 1999
Issue: 5 Volume: 6 Page: 342-8

Laboratory markers of platelet activation and their clinical significance. 

Michelson A, Furman MI
Journal Article: Transfusion Year: 1999
Issue: 8 Volume: 39 Page: 880-8

Fresh, liquid-preserved, and cryopreserved platelets: adhesive surface receptors and membrane procoagulant activity. 

Barnard MR, MacGregor H, Ragno G, Pivacek LE, Khuri SF, Michelson A, Valeri CR
Journal Article: Transfusion Year: 1999
Issue: 7 Volume: 39 Page: 735-41

Platelet surface p-selectin, platelet-granulocyte heterotypic aggregates, and plasma-soluble p-selectin during plateletpheresis. 

Barnard MR, MacGregor H, Mercier R, Ragno G, Pivacek LE, Hechtman HB, Michelson A, Valeri CR
Journal Article: The Journal of thoracic and cardiovascular surgery Year: 1999
Issue: 1 Volume: 117 Page: 172-83; discussion 183-4

Comparison of the effects of transfusions of cryopreserved and liquid-preserved platelets on hemostasis and blood loss after cardiopulmonary bypass. 

Khuri SF, Healey N, MacGregor H, Barnard MR, Szymanski IO, Birjiniuk V, Michelson A, Gagnon DR, Valeri CR
Journal Article: British journal of haematology Year: 1999
Issue: 1 Volume: 104 Page: 64-8

The effects of aspirin and hypothermia on platelet function in vivo. 

Michelson A, Barnard MR, Khuri SF, Rohrer MJ, MacGregor H, Valeri CR
Journal Article: Chest Year: 1998
Issue: 5 Suppl Volume: 114 Page: 748S-769S

Antithrombotic therapy in children. 

Michelson A, Bovill E, Monagle P, Andrew M
Journal Article: American journal of kidney diseases : the official journal of the National Kidney Foundation Year: 1998
Issue: 1 Volume: 32 Page: 132-8

Elevated plasma glycocalicin levels and decreased ristocetin-induced platelet agglutination in hemodialysis patients. 

Himmelfarb J, Nelson S, McMonagle E, Holbrook D, Benoit SE, Michelson A, Ault K
Journal Article: Journal of vascular surgery Year: 1998
Issue: 6 Volume: 27 Page: 1109-15; discussion 1115-6

Patients with venous stasis ulceration have increased monocyte-platelet aggregation. 

Peyton BD, Rohrer MJ, Furman MI, Barnard MR, Rodino LJ, Benoit SE, Hechtman HB, Valeri CR, Michelson A
Journal Article: Thrombosis and haemostasis Year: 1998
Issue: 5 Volume: 79 Page: 885-96

European Working Group on Clinical Cell Analysis: Consensus protocol for the flow cytometric characterisation of platelet function. 

Schmitz G, Rothe G, Ruf A, Barlage S, Tschöpe D, Clemetson KJ, Goodall AH, Michelson A, Nurden AT, Shankey TV
Journal Article: The Journal of pediatrics Year: 1998
Issue: 4 Volume: 132 Page: 575-88

Guidelines for antithrombotic therapy in pediatric patients. 

Andrew M, Michelson A, Bovill E, Leaker M, Massicotte MP
Journal Article: Proceedings of the National Academy of Sciences of the United States of America Year: 1998
Issue: 6 Volume: 95 Page: 3082-7

The cleaved peptide of the thrombin receptor is a strong platelet agonist. 

Furman MI, Liu L, Benoit SE, Becker R, Barnard MR, Michelson A
Journal Article: Journal of the American College of Cardiology Year: 1998
Issue: 2 Volume: 31 Page: 352-8

Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease. 

Furman MI, Benoit SE, Barnard MR, Valeri CR, Borbone ML, Becker R, Hechtman HB, Michelson A
Journal Article: Seminars in thrombosis and hemostasis Year: 1998
Issue: 6 Volume: 24 Page: 507-12

Platelet function in the newborn. 

Michelson A
Journal Article: The Journal of clinical investigation Year: 1997
Issue: 2 Volume: 100 Page: 350-6

Nitric oxide released from activated platelets inhibits platelet recruitment. 

Freedman JE, Loscalzo J, Barnard MR, Alpert C, Keaney JF, Michelson A
Journal Article: Thrombosis and haemostasis Year: 1997
Issue: 5 Volume: 77 Page: 1002-7

Platelet hyporeactivity in very low birth weight neonates. 

Rajasekhar D, Barnard MR, Bednarek FJ, Michelson A
Journal Article: Platelets Year: 1997
Issue: 2-3 Volume: 8 Page: 105-15

Flow cytometric assessment of glycoprotein movements in platelets. 

Michelson A
Journal Article: Journal of pediatric hematology/oncology Year: 1997
Issue: 1 Volume: 19 Page: 7-22

The prevention and treatment of thromboembolic disease in children: a need for Thrombophilia Programs. 

Andrew M, Michelson A, Bovill T, Leaker M, Massicotte P, Marzinotto V, Brooker LA
Journal Article: Proceedings of the National Academy of Sciences of the United States of America Year: 1996
Issue: 21 Volume: 93 Page: 11877-82

In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. 

Michelson A, Barnard MR, Hechtman HB, MacGregor H, Connolly RJ, Loscalzo J, Valeri CR
Journal Article: The Journal of thoracic and cardiovascular surgery Year: 1996
Issue: 4 Volume: 112 Page: 1098-107

Reduction of bleeding after heart operations through the prophylactic use of epsilon-aminocaproic acid. 

Vander Salm TJ, Kaur S, Lancey RA, Okike ON, Pezzella AT, Stahl RF, Leone L, Li JM, Valeri CR, Michelson A
Journal Article: Academic radiology Year: 1996
Volume: 3 Suppl 3 Page: S485-7

Variability of platelet degranulation by different contrast media. 

Grabowski EF, Jang IK, Gold H, Head C, Benoit SE, Michelson A
Journal Article: The American journal of physiology Year: 1996
Issue: 2 Pt 2 Volume: 271 Page: H528-34

Effect of heparin on fibrinolytic activity and platelet function in vivo. 

Upchurch GR, Valeri CR, Khuri SF, Rohrer MJ, Welch GN, MacGregor H, Ragno G, Francis S, Rodino LJ, Michelson A, Loscalzo J
Journal Article: Academic radiology Year: 1996
Volume: 3 Suppl 2 Page: S328-30

Platelets are degranulated by some, but not all, contrast media. 

Grabowski EF, Boor SE, Rodino LJ, Jang IK, Gold H, Michelson A
Journal Article: Blood Year: 1996
Issue: 12 Volume: 87 Page: 4925-36

Flow cytometry: a clinical test of platelet function. 

Michelson A
Journal Article: The American journal of physiology Year: 1996
Issue: 5 Pt 2 Volume: 270 Page: H1640-8

Effects of nitric oxide/EDRF on platelet surface glycoproteins. 

Michelson A, Benoit SE, Furman MI, Breckwoldt WL, Rohrer MJ, Barnard MR, Loscalzo J
Journal Article: The Journal of surgical research Year: 1996
Issue: 2 Volume: 61 Page: 543-8

Adhesion of activated platelets to venous endothelial cells is mediated via GPIIb/IIIa. 

Li JM, Podolsky RS, Rohrer MJ, Cutler BS, Massie MT, Barnard MR, Michelson A
Journal Article: The Journal of clinical investigation Year: 1996
Issue: 4 Volume: 97 Page: 979-87

Decreased platelet inhibition by nitric oxide in two brothers with a history of arterial thrombosis. 

Freedman JE, Loscalzo J, Benoit SE, Valeri CR, Barnard MR, Michelson A
Journal Article: The New England journal of medicine Year: 1995
Issue: 16 Volume: 333 Page: 1051

Images in clinical medicine. A morphologic question. 

Barnard MR, Michelson A
Journal Article: Chest Year: 1995
Issue: 4 Suppl Volume: 108 Page: 506S-522S

Antithrombotic therapy in children. 

Michelson A, Bovill E, Andrew M
Journal Article: Circulation Year: 1995
Issue: 6 Volume: 92 Page: 1399-407

Fibrinolysis inhibits shear stress-induced platelet aggregation. 

Kamat SG, Michelson A, Benoit SE, Moake JL, Rajasekhar D, Hellums JD, Kroll MH, Schafer AI
Journal Article: Acta radiologica. Supplementum Year: 1995
Volume: 399 Page: 182-4

Platelet degranulation induced by some contrast media is independent of their nonionic vs ionic nature. 

Grabowski EF, Jang IK, Gold H, Palacios IF, Boor SE, Rodino LJ, Michelson A
Journal Article: Thrombosis and haemostasis Year: 1994
Issue: 6 Volume: 72 Page: 957-63

Neonatal platelets are less reactive than adult platelets to physiological agonists in whole blood. 

Rajasekhar D, Kestin AS, Bednarek FJ, Ellis PA, Barnard MR, Michelson A
Journal Article: Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association Year: 1994
Issue: 7 Volume: 14 Page: 1193-201

Platelet activation results in a redistribution of glycoprotein IV (CD36). 

Michelson A, Wencel-Drake JD, Kestin AS, Barnard MR
Journal Article: Blood Year: 1994
Issue: 12 Volume: 83 Page: 3562-73

The activation-induced decrease in the platelet surface expression of the glycoprotein Ib-IX complex is reversible. 

Michelson A, Benoit SE, Kroll MH, Li JM, Rohrer MJ, Kestin AS, Barnard MR
Journal Article: Investigative radiology Year: 1994
Volume: 29 Suppl 2 Page: S198-200

Effects of contrast media on platelet activation using flowing whole blood aggregometry and flow cytometry of platelet membrane glycoproteins. 

Grabowski EF, Head C, Michail HA, Jang IK, Gold H, Benoit SE, Michelson A
Journal Article: Thrombosis and haemostasis Year: 1994
Issue: 5 Volume: 71 Page: 633-40

Reversible inhibition of human platelet activation by hypothermia in vivo and in vitro. 

Michelson A, MacGregor H, Barnard MR, Kestin AS, Rohrer MJ, Valeri CR
Journal Article: Journal of vascular surgery Year: 1994
Issue: 2 Volume: 19 Page: 306-18; discussion 318-9

Human neutrophil cathepsin G is a potent platelet activator. 

LaRosa CA, Rohrer MJ, Benoit SE, Rodino LJ, Barnard MR, Michelson A
Journal Article: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis Year: 1994
Issue: 1 Volume: 5 Page: 121-31

Platelet activation by thrombin can be directly measured in whole blood through the use of the peptide GPRP and flow cytometry: methods and clinical applications. 

Michelson A
Journal Article: British journal of haematology Year: 1993
Issue: 3 Volume: 85 Page: 533-41

Aprotinin reduces cardiopulmonary bypass-induced blood loss and inhibits fibrinolysis without influencing platelets. 

Orchard MA, Goodchild CS, Prentice CR, Davies JA, Benoit SE, Creighton-Kemsford LJ, Gaffney PJ, Michelson A
Journal Article: Investigative radiology Year: 1993
Volume: 28 Suppl 5 Page: S21-4

Nonionic contrast media. Procoagulants or clotting innocents? 

Grabowski EF, Head C, Michelson A
Journal Article: Circulation Year: 1993
Issue: 4 Pt 1 Volume: 88 Page: 1502-11

Effect of strenuous exercise on platelet activation state and reactivity. 

Kestin AS, Ellis PA, Barnard MR, Errichetti A, Rosner BA, Michelson A
Journal Article: Journal of vascular surgery Year: 1992
Issue: 6 Volume: 15 Page: 1000-8; discussion 1008-9

High-dose heparin suppresses platelet alpha granule secretion. 

Rohrer MJ, Kestin AS, Ellis PA, Barnard MR, Rodino L, Breckwoldt WL, Li JM, Michelson A
Journal Article: Seminars in thrombosis and hemostasis Year: 1992
Issue: 1 Volume: 18 Page: 18-27

Thrombin-induced down-regulation of the platelet membrane glycoprotein Ib-IX complex. 

Michelson A
Journal Article: American journal of hematology Year: 1991
Issue: 2 Volume: 38 Page: 145-6

Thrombocytopenia associated with environmental exposure to polyurethane. 

Michelson A
Journal Article: Thrombosis research Year: 1991
Issue: 4 Volume: 63 Page: 427-32

Platelet glycogen synthase: further characterization and effect of insulin. 

Matic GB, Jaspers SR, Miller T, Michelson A
Journal Article: Blood Year: 1991
Issue: 8 Volume: 77 Page: 1740-8

Glycoprotein Ib (GPIb)-dependent and GPIb-independent pathways of thrombin-induced platelet activation. 

Yamamoto N, Greco NJ, Barnard MR, Tanoue K, Yamazaki H, Jamieson GA, Michelson A
Journal Article: Blood Year: 1991
Issue: 4 Volume: 77 Page: 770-9

Downregulation of the platelet surface glycoprotein Ib-IX complex in whole blood stimulated by thrombin, adenosine diphosphate, or an in vivo wound. 

Michelson A, Ellis PA, Barnard MR, Matic GB, Viles AF, Kestin AS
Journal Article: Thrombosis research Year: 1990
Issue: 5 Volume: 60 Page: 421-4

Effect of in vivo infusion of recombinant tissue-type plasminogen activator on platelet glycoprotein Ib. 

Michelson A, Gore JM, Rybak ME, Cola CA, Barnard MR
Journal Article: Blood Year: 1990
Issue: 10 Volume: 76 Page: 2005-10

Plasmin-induced redistribution of platelet glycoprotein Ib. 

Michelson A, Barnard MR
Journal Article: The American journal of pediatric hematology/oncology Year: 1989
Issue: 1 Volume: 11 Page: 44-5

Chemotherapy-induced painful acral erythema in childhood: Burgdorf's reaction. 

Burke MC, Bernhard JD, Michelson A
Journal Article: The Journal of clinical investigation Year: 1988
Issue: 6 Volume: 81 Page: 1734-40

Platelet storage results in a redistribution of glycoprotein Ib molecules. Evidence for a large intraplatelet pool of glycoprotein Ib. 

Michelson A, Adelman B, Barnard MR, Carroll E, Handin RI
Journal Article: Progress in clinical and biological research Year: 1988
Volume: 283 Page: 131-6

Flow cytometric detection of distinct subpopulations of platelets in individual patients. 

Michelson A
Journal Article: Progress in clinical and biological research Year: 1988
Volume: 283 Page: 159-62

Thrombin-induced changes in platelet membrane glycoproteins. 

Michelson A, Barnard MR
Journal Article: Blood Year: 1987
Issue: 5 Volume: 70 Page: 1673-8

Thrombin-induced changes in platelet membrane glycoproteins Ib, IX, and IIb-IIIa complex. 

Michelson A, Barnard MR
Journal Article: The Journal of laboratory and clinical medicine Year: 1987
Issue: 3 Volume: 110 Page: 346-54

Flow cytometric analysis of platelet surface glycoproteins: phenotypically distinct subpopulations of platelets in children with chronic myeloid leukemia. 

Michelson A
Journal Article: The American journal of pediatric hematology/oncology Year: 1987
Issue: 2 Volume: 9 Page: 161-3

Transient neurological disorder associated with transient erythroblastopenia of childhood. 

Michelson A, Marshall PC
Journal Article: Blood Year: 1986
Issue: 6 Volume: 68 Page: 1280-4

Proteolysis of platelet glycoprotein Ib by plasmin is facilitated by plasmin lysine-binding regions. 

Adelman B, Michelson A, Greenberg J, Handin RI
Journal Article: Blood Year: 1986
Issue: 1 Volume: 67 Page: 19-26

Partial characterization of a binding site for von Willebrand factor on glycocalicin. 

Michelson A, Loscalzo J, Melnick B, Coller BS, Handin RI
Journal Article: Blood Year: 1985
Issue: 2 Volume: 66 Page: 423-7

Evaluation of platelet glycoprotein Ib by fluorescence flow cytometry. 

Adelman B, Michelson A, Handin RI, Ault KA
Journal Article: Blood Year: 1985
Issue: 1 Volume: 65 Page: 32-40

Plasmin effect on platelet glycoprotein Ib-von Willebrand factor interactions. 

Adelman B, Michelson A, Loscalzo J, Greenberg J, Handin RI
Journal Article: Australian paediatric journal Year: 1984
Issue: 4 Volume: 20 Page: 333-5

Haemolytic anaemia associated with acquired toxoplasmosis. 

Michelson A, Lammi AT